Characterization of microglia/macrophages in gliomas developed in S‐100β‐v‐erbB transgenic rats

January 20, 2013, from MedWorm: Brain Tumor

In conclusion, S‐100β‐v‐erbB TG rats may serve as a useful animal model for further analysis of TAMs in terms of tumor cell proliferation, microvascular proliferation and phagocytosis, and as a tool for therapeutic use in malignant gliomas, although it should be noted that the polarization of TAMs toward the M2 phenotype remains unclear. (Source: Neuropathology) View Source