A Young Man with a Twitching Arm (P02.073)
CONCLUSIONS: Clinical features of patient's crisis characterized by facial twitching, dysarthria and hand posturing resembled "faciobrachial dystonic seizures", a recently described entity that occurs almost exclusively in association with LGI-1 antibodies1. The recognition of this clinical phenotype is critical because the response to anti-epileptic drugs is unsatisfactory while response to immunotherapy is excellent. Moreover early initiation of immunosuppressant therapy offers the chance to modify the course of this neurological disorder avoiding the development of full-blown limbic encephalitis. Here we document also that contrast-enhancing lesions involving basal ganglia can be associated with FBDS and LGI-1 antibodies.Disclosure: Dr. Plantone has nothing to disclose. Dr. Renna has no...
