A Comparison of Two Doses of Mannitol on Brain Relaxation During Supratentorial Brain Tumor Craniotomy: A Randomized Trial.

January 25, 2013, from MedWorm: Brain Tumor

CONCLUSION:In this study, we show that 1.4 g·kg(-1) of 20% mannitol results in equivalent brain relaxation scores as 0.7 g·kg(-1) in patients undergoing craniotomy for supratentorial brain tumor. When corrected for the presence of midline shift, this study reveals that patients in the high-dose group had significantly more chances of obtaining a better relaxation score compared with the lower-dose group. PMID: 23354336 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia) View Source