Subcortical damage is ‘primary cause’ of neurological deficits after ‘awake craniotomy’

(Wolters Kluwer Health) Injury to the subcortical structures of the inner brain is a major contributor to worsening neurological abnormalities after “awake craniotomy” for brain tumors, reports a study in the February issue of Neurosurgery, official journal of the Congress of Neurological Surgeons. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health. (Source: EurekAlert! – Medicine and Health)

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The epidemiology of intermittent and chronic ataxia in children in Manitoba, Canada

AimTo determine the epidemiology of chronic ataxia in children in Manitoba, Canada.
MethodA retrospective study using multiple sources and disease codes identified children (age 0–16y) with chronic ataxia (>2mo duration or recurrent episodes of ataxia) seen at Winnipeg Children’s Hospital from 1991 to 2008. Patients with isolated peripheral nerve diseases, vestibular disorders, or brain tumors were excluded.
ResultsWe identified 184 patients (males=females; mean age 15y, SD 7y 8mo) with chronic ataxia. Median age at the presenting symptom onset was 1 year 3 months and at ataxia onset 3 years 1 month. Median duration of follow‐up was 6 years 5 months. During the study period, the crude incidence rate was 5.77 in 10 000; the crude prevalence rate was 6.59 in 10 000; and the cr…

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Effects of perfusion on diffusion changes in human brain tumors

Conclusion:The ability to accurately identify changes in diffusion on traditional FDMs is confounded in areas where perfusion and diffusion changes are colocalized. Flow‐compensated FDMs, which use only non‐zero b‐values, should therefore be the standard approach. J. Magn. Reson. Imaging 2013;. © 2013 Wiley Periodicals, Inc. (Source: Journal of Magnetic Resonance Imaging)

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