Tumors of the Central Nervous System, Volume 9

Lymphoma, Supratentorial Tumors, Glioneuronal Tumors, Gangliogliomas, Neuroblastoma in Adults, Astrocytomas, Ependymomas, Hemangiomas, and Craniopharyngiomasseries:Tumors of the Central Nervous SystemThe ninth volume in this essential series discusses …

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Health Care Professionals’ Evaluation of Quality Of Life Issues in Patients with Brain Metastases

The Functional Assessment of Cancer Therapy – Brain (FACT-Br) is a brain specific Quality of life (QOL) tool used for both the primary brain tumour as well as metastatic brain tumour patient population. The purpose of this report is to evaluate the QOL issues health care professionals (HCPs) find most important when caring for brain metastases patients. (Source: Journal of Medical Imaging and Radiation Sciences)

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Even With Brain Mapping, Damage To Inner Brain Structures Can Occur During Conscious Brain Surgery

Injury to the subcortical structures of the inner brain is a major contributor to worsening neurological abnormalities after “awake craniotomy” for brain tumors, reports a study in the February issue of Neurosurgery, official journal of the Congress of Neurological Surgeons. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health. During a procedure intended to protect critical functional areas in the outer brain (cortex), damage to subcortical areas – which may be detectable on MRI scans – is a major risk factor for persistent neurological deficits… (Source: Health News from Medical News Today)

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Safety Profile, Efficacy, and Biodistribution of a Bicistronic High-Capacity Adenovirus Vector Encoding a Combined Immunostimulation and Cytotoxic Gene Therapy as a Prelude to a Phase I Clinical Trial for Glioblastoma.

We reported the efficacy of a gene therapy approach for glioma consisting of intratumoral injection of Ads encoding conditionally cytotoxic herpes simplex type 1 thymidine kinase (Ad-TK) and the immunostimulatory cytokine fms-like tyrosine kinase ligan…

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